Ikaros DNA-Binding Proteins Direct Formation of Chromatin Remodeling Complexes in Lymphocytes
نویسندگان
چکیده
منابع مشابه
Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.
Ikaros is a sequence-specific DNA-binding protein that is essential for lymphocyte development. Little is known about the molecular function of Ikaros, although recent results have led to the hypothesis that it recruits genes destined for heritable inactivation to foci containing pericentromeric heterochromatin. To gain further insight into the functions of Ikaros, we have examined the mechanis...
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ژورنال
عنوان ژورنال: Immunity
سال: 1999
ISSN: 1074-7613
DOI: 10.1016/s1074-7613(00)80034-5